Four puzzle solutions reveal different ways to divine someone’s hidden number with impossibly little information.

The second law of thermodynamics is among the most sacred in all of science, but it has always rested on 19th century arguments about probability. New arguments trace its true source to the flows of quantum information.

A bit of information theory can help you analyze — and improve — your Wordle game.

RNA and peptides coevolving in the primordial world might have jointly served as a precursor to the modern ribosome.

Why verify every line of a proof, when just a few checks will do?

Synthetic biology experiments suggest a “MultiFate” model for how genetically identical cells become the many different types found in complex organisms like us.

The space telescope is one of the most ambitious scientific projects ever undertaken. Marcia Rieke and Nikole Lewis, two of the scientists leading JWST investigations, talk to Steven Strogatz about how it may transform our understanding of the universe.

“Ribbon concordance” will let mathematicians compare knots by linking them across four-dimensional space.

Leslie Lamport revolutionized how computers talk to each other. Now he’s working on how engineers talk to their machines.