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Genomics

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He’s Gleaning the Design Rules of Life to Re-Create It

November 4, 2024

Yizhi “Patrick” Cai is coordinating a global effort to write a complete synthetic yeast genome. If he succeeds, the resulting cell will be the artificial life most closely related to humans to date.

Q&A

The Viral Paleontologist Who Unearths Pathogens’ Deep Histories

August 16, 2024

Sébastien Calvignac-Spencer searches museum jars for genetic traces of flu, measles and other viruses. Their evolutionary stories can help treat modern outbreaks and prepare for future ones.

The Quest for Simple Rules to Build a Microbial Community

January 17, 2024

Microbiologists are searching for a universal theory of how bacteria form communities based not on their species but on the roles they play.

To Defend the Genome, These Cells Destroy Their Own DNA

September 26, 2023

Under a microscope, cells in a worm embryo deliberately eliminated one-third of their genome — an uncompromising tactic that may combat harmful genetic parasites.

Selfish, Virus-Like DNA Can Carry Genes Between Species

August 3, 2023

Genetic elements called Mavericks that have some viral features could be responsible for the large-scale smuggling of DNA between species.

How Genetic Surprises Complicate the Old Doctrine of DNA

July 31, 2023

For over a century, biologists have had to contend with a complicated picture of genetics, which they’ve only recently begun to understand.

How 3D Changes in the Genome Turned Sharks Into Skates

May 30, 2023

Changes in the 3D structure of their genome gave skates and rays their distinctive winglike fins and pancake flatness.

Q&A

She Tracks the DNA of Elusive Species That Hide in Harsh Places

April 17, 2023

On Mount Everest and in the Peruvian Andes, Tracie Seimon uses DNA to study how species and ecosystems respond to climate change, pathogens and other influences.

Animal Mutation Rates Reveal Traits That Speed Evolution

April 5, 2023

The first large-scale comparison of mutation rates gives insights into how quickly species can evolve.

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