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How Spiders Spin ‘Silk Dope’ Into Nature’s Toughest Material
By probing its molecular structure, biologists are uncovering how a tangle of unstructured proteins turns into a strong, flexible fiber.
Malaria Parasite Caught in the Act of Breaking and Entering
To invade red blood cells, the deadly protist creates a temporary molecular portal that disappears behind it — a door we can now see in fine detail.
Why Aging May Be a Program, Not a Breakdown
By deciphering the molecular signatures of millions of mouse cells, Junyue Cao has found that aging is not haphazard wear and tear but rather a “remodeling of the cell society.”
Why the Human Genome’s Tangled Physicality May Confound AI
Our genetic heritage is not a blueprint or an algorithm, as many biologists have imagined, but something else entirely.
What Physical ‘Life Force’ Turns Biology’s Wheels?
The bacterial flagellar motor is finally understood after 50 years. In its workings, columnist Natalie Wolchover finds the essence of life.
The Ancient Weapons Active in Your Immune System Today
Dozens of new discoveries reveal that defenses evolved by bacteria and viruses billions of years ago still define our own innate immune system.
Disorder Drives One of Nature’s Most Complex Machines
Every second, hundreds to thousands of molecules move through thousands of nuclear pores in each of your cells. A new high-definition view reveals the machine in action.
The Biophysical World Inside a Jam-Packed Cell
Innovations in imaging and genetic engineering are coming together to probe the biophysics of cytoplasm inside living animals.
The Microbial Masters of Earth’s Climate
A collection of short dispatches from the field of climate microbiology conveys the contributions that single-celled life forms make to our climate system, and how we can work with them to address climate change.