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The Mysterious Flow of Fluid in the Brain
A popular hypothesis for how the brain clears molecular waste, which may help explain why sleep feels refreshing, is a subject of debate.
How Metabolism Can Shape Cells’ Destinies
A growing body of work suggests that cell metabolism — the chemical reactions that provide energy and building materials — plays a vital, overlooked role in the first steps of life.
How Did Multicellular Life Evolve?
One of the most important events in the history of life on Earth was the emergence of multicellularity. In this episode, Will Ratcliff discusses how his snowflake yeast models provide insight into what drove the transition from single-celled to multicellular organisms.
A New, Chemical View of Ecosystems
Rare and powerful compounds, known as keystone molecules, can build a web of invisible interactions among species.

The ‘Elegant’ Math Model That Could Help Rescue Coral Reefs
Physicists and marine biologists built a quantitative framework that predicts how coral polyps collectively construct a variety of coral shapes.
How ‘Event Scripts’ Structure Our Personal Memories
By screening films in a brain scanner, neuroscientists discovered a rich library of neural scripts — from a trip through an airport to a marriage proposal — that form scaffolds for memories of our experiences.
The Poetry Fan Who Taught an LLM to Read and Write DNA
By treating DNA as a language, Brian Hie’s “ChatGPT for genomes” could pick up patterns that humans can’t see, accelerating biological design.
How Does Life Happen When There’s Barely Any Light?
Under the sea ice during the Arctic’s pitch-black polar night, cells power photosynthesis on the lowest light levels ever observed in nature.
Concept Cells Help Your Brain Abstract Information and Build Memories
Individual cells in the brain light up for specific ideas. These concept neurons, once known as “Jennifer Aniston cells,” help us think, imagine and remember episodes from our lives.